Agent Substrate is a secure-by-default agent execution runtime engineered to run millions of sandboxes with 10x higher density than standard container runtimes. Purpose-built for the era of autonomous agents, Substrate delivers sub-500ms resume operations at over 500 suspend/resume activations per second with native zero-trust kernel and network isolation. It supports multiple sandbox technologies including microVMs and gVisor, enabling consistent lifecycle operations for all sandbox types. At its core, Agent Substrate maps a larger set of “actors” (applications such as agents) onto a smaller